Solubilisation of cholesterol in human bile
نویسندگان
چکیده
منابع مشابه
Occurrence of cholesterol crystals in human bile.
The occurrence of cholesterol crystals was studied in 20 consecutive gallstone patients with functioning gallbladders. The frequency with which crystals were found rose sharply with the number of stones. Gallbladder bile was found more often to contain cholesterol crystals than hepatic bile of the same individual. Such crystals were absent in T tube drain bile from 10 consecutive choledochostom...
متن کاملQuantitation of cholesterol-carrying particles in human gallbladder bile.
The inter-mixed micellar/vesicular (non-phospholipid-associated) bile salt concentration (IMC) can be rapidly measured in model biles by centrifugal ultrafiltration, thus allowing reliable separation of vesicular and micellar cholesterol carriers by gel filtration with an elution buffer containing bile salts at the correct IMC (Donovan, J. M., and A. A. Jackson. 1993. J. Lipid Res. 34: 1121-112...
متن کاملStudies of Gallbladder Function. Xv. Cholesterol in Human Liver Bile.
The subject of bile drainage in the human has been very thoroughly reviewed by Fox (1) in 1928. Numerous papers have appeared, among which may be mentioned those of Walters, Green and Frederickson (2), Ravdin, Johnston, Riegel and Wright (3), and Elman and Graham (4), describing the changes occurring in hepatic bile obtained from patients with surgical drainage after the release of biliary obst...
متن کاملIi. Bile Cholesterol
Under uniform diet conditions the normal bile fistula dog will eliminate pretty constant amounts of cholesterol-about 0.5 to 1.0 mg. cholesterol per kilo per 24 hours. Diets rich in cholesterol (egg yolk) will raise the cholesterol output in the bile but compared to the diet intake (1.5 gm. cholesterol) the output increase in the bile is trivial (5-15 mg.). Calves' brains in the diet are inert....
متن کاملAssociation between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile.
Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation. We examined the amount of these vesicles in 33 human gallbladder biles in relation to biliary lipid composition and to the presence of cholesterol crystals. Biliary microscopy detected cholesterol cr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Letters
سال: 1985
ISSN: 0014-5793
DOI: 10.1016/0014-5793(85)80288-x